Holders Barcelona will face fellow Spaniards Atletico Madrid, runners-up two seasons ago, in the Champions League quarter-finals following the draw in Nyon on Friday.
Football action from across Europe in matches played on Saturday
While it is unfair to blame the Wales winger for all of Real's recent woes, it cannot be denied that he appears to be struggling for form and confidence.
IMAGES from soccer matches played across Europe on Sunday.
Images from the UEFA Champions League matches played on Wednesday night.
Atletico Madrid took a giant step towards the La Liga title
Real Madrid's early-season woes deepened when they lost 2-1 at home to La Liga champions Atletico Madrid, while substitute Neymar struck twice in Barcelona's 2-0 win against visiting Athletic Bilbao on Saturday.
After falling 2-0 down on the night, substitute Marcos Llorente struck twice in extra-time and Alvaro Morata added a late third to ensure a famous victory for Diego Simeone's side against a Liverpool team unbeaten in their last 25 home games in European competition.
Costa turned Juanfran's low cross into the net in the 69th minute for Atletico's third goal in the first leg of the last 16 tie against third division Lleida but immediately limped to the sidelines. He did return to the pitch, however, and completed the game despite bleeding from his knee.
Real Madrid's consistency and hard work made them worthy La Liga champions, captain Sergio Ramos said after their 2-0 win at Malaga on Sunday ended a five-year wait for the title.
Leverkusen's Schick scores hat-trick in comeback win over Heidenheim.
Goalkeeper Ivan Provedel scored in the dying moments of the Champions League Group E match against Atletico Madrid, heading home the equaliser, to earn Lazio a 1-1 draw at Stadio Olimpico, in Rome, on Tuesday.
Vietto slotted the ball home with seven minutes to go after Karim Benzema had given visitors Real the lead early on.
A round-up of Tuesday's action in the UEFA Champions League.
Robert Lewandowski and Raphinha both scored twice to help Barcelona thrash hosts Villarreal 5-1.
Manchester City came from behind to beat Club Brugge 3-1 and secure their place in the Champions League playoffs
At the moment I don't see me having an expiry date, I'd love to stay here for many years to come, says Real Madrid manager Carlo Ancelotti, who'll be completing a landmark on Tuesday.
Spanish soccer's 'El Clasico' encounters between Barcelona and Real Madrid will happen in December and April, two of the most anticipated games of the 2016-17 Primera Division season whose fixtures were announced on Friday. Defending champions Barca host Real on Dec. 4 at the Camp Nou. The reverse fixture will take place on April 23, at the Bernabeu stadium, the Spanish Football Federation (RFEF) confirmed after the draw. As the La Liga season kicks off, Barca will begin their title defence at home to Real Betis on Aug. 21.
Having absorbed the body blow of losing striker Radamel Falcao in the close season, Atletico Madrid have emerged as genuine contenders to break the title stranglehold of Real Madrid and Barcelona.
IMAGES from the Europa League matches played on Thursday
Defending champions Bayern Munich must face Diego Simeone's Atletico Madrid after they were drawn together in Champions League Group A alongside Salzburg and Lokomotiv Moscow.
It was Messi's 30th goal in 39 competitive games against Atletico
Real Madrid's unbeaten start to the La Liga season came to an abrupt and surprising end as Real Mallorca claimed a stunning 1-0 victory at a rocking Son Moix on Saturday to climb out of the relegation zone.
Inter Milan have completed the signing of Brazil centre back Miranda from Atletico Madrid as they look to shore up a defence that struggled during a disappointing 2014-15 season.
Barca had been trying to sign the 21-year-old right back for $6.5 million in a deal
Atletico Madrid earned a 1-1 draw away to Girona in a chaotic and entertaining Copa del Rey last 16 first-leg match on Wednesday, leaving the tie finely balanced.
Images from matches played across top football leagues in Europe.
The underdogs kept their noses in front as Liverpool beat Manchester City 3-2 to stay top of the Premier League and Atletico Madrid won 2-0 at Getafe to increase their lead in La Liga after Barcelona slipped up at lowly Granada. Read on to meet the players of the weekend...
With Real Madrid facing an injury crisis ahead of Wednesday's Champions League clash with Atletico Madrid attention will be on talisman Cristiano Ronaldo to lead them through but James Rodriguez may hold the key.
Lionel Messi came to Barcelona's rescue for the second time in a week by snatching a late winner to give his side a barely deserved 2-1 win at Atletico Madrid on Sunday which provisionally took the champions top of La Liga.
Real Madrid defender Marcelo says the club needed new direction after stuttering under Rafael Benitez and has praised Zinedine Zidane for 'breathing life back' into the team since taking over as coach in January.
Barca looked set for a third consecutive league draw as they created scant opportunities but they were presented with the advantage of an extra man when Villarreal midfielder Daniel Raba was given a straight red card for a wild, studs-up challenge on Sergio Busquets on the hour mark.
Thomas Partey scored his first goal for Atletico Madrid as they reached the last 16 of the King's Cup with a 1-0 home victory over third-tier Reus on Thursday that secured a 3-1 aggregate success.
Real Madrid fought back from two goals down as Vinicius Jr grabbed a hat-trick in a thrilling 5-2 win over visitors Borussia Dortmund in the Champions League.
Sevilla drew level on points with Barcelona at the top of La Liga when they snatched a 2-1 comeback victory at home to Villarreal, while champions Atletico Madrid won 1-0 in a bad-tempered clash at Getafe on Sunday.
Cristiano Ronaldo ensured Atletico Madrid fans will have bitter memories of the last local derby at the Vicente Calderon stadium by scoring a hat-trick in a 3-0 win for La Liga leaders Real Madrid on Saturday. Ronaldo's deflected free kick put Real in charge in the 23rd minute in the first meeting of the teams since the Champions League final in May. The prolific Portuguese killed off Atletico's resistance by winning and converting a penalty in the 71st minute and capped a harrowing night for the home side by tapping in the third in the 77th.
Real Madrid president Florentino Perez has ruled out an immediate return of the recently sacked Chelsea manager Jose Mourinho despite having `good memories` under the Portuguese's tenure in the club.
Real Madrid star striker Cristiano Ronaldo has extended his apology to teammates for his controversial remark that the club would be at the top of La Liga if every player was on his level.
Barcelona closed in on the La Liga title after beating 10-man Atletico Madrid 2-0 in Saturday's top-of-the-table showdown at the Nou Camp as late strikes by Luis Suarez and Lionel Messi gave the Catalans an 11-point lead at the top of the table.
Champions Barcelona begin their bid for a sixth La Liga title in eight years at Athletic Bilbao on Sunday knowing that fellow heavyweights Real Madrid could, unusually, be just one of several challengers for their crown.